Real Betis got an away win at the Estadio de la Cerámica after playing down to ten men since Chimy Ávila was sent off in the 30th minute. 

Vitor Roque and Lo Celso put the Verdiblancos in front before Álex Baena scored the only goal for the guests. 

Villarreal CF: Luiz Júnior, Kiko Femenía, Raúl Albiol, Eric Bailly (Juan Bernat 46'), Sergi Cardona, Yéremy Pino (Pau Cabanes 70'), Pape Gueye (Thierno Barry 57'), Dani Parejo, Álex Baena, Ayoze y Gerard Moreno.

Real Betis Balompié: Fran Vieites, Sabaly, Bartra, Llorente, Perraud, Altimira (Natan 88'), Johnny, Chimy, Lo Celso (Isco 74'), Ez Abde (Aitor Ruibal 74') y Vitor Roque (Assane Diao 67'). 

Goals: 0-1 (32') Vitor Roque; 0-2 (47') Lo Celso; 1-2 (55') Álex Baena.

Referee: Cuadra Fernández. Booked with a yellow Villarreal's Pape Gueye, Kike Femenía, Álex Baena, Yéremy Pino and Dani Parejo and Real Betis' Bakambu, Aitor Ruibal, Vitor Roque and Lo Celso. The referee also sent off Chimy with a straight red card.